Sabatino Di Mascio began his classical guitar studies at the L. Refice Conservatory in Frosinone. He continued his career by obtaining the academic diploma in Classical Guitar at the Santa Cecilia Conservatory in Rome under Antonio De Rose's guidance.
He held concerts in the Vatican presenting his Works dedicated to Pope Wojtyla and Pope Emeritus Joseph Ratzinger. He composed several songs for RAI and director Michele Piacentini. Di Mascio recorded for Vatican Radio. His music is known and appreciated in Canada and America.